: MeSH: Uncoupling Agents

Chemical Actions and Uses > Pharmacologic Actions > Molecular Mechanisms of Pharmacological Action > Enzyme Inhibitors > Uncoupling Agents

Uncoupling Agents

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Chemical agents that uncouple oxidation from phosphorylation in the metabolic cycle so that ATP synthesis does not occur. Included here are those IONOPHORES that disrupt electron transfer by short-circuiting the proton gradient across mitochondrial membranes.

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