: MeSH: Pancreatitis-Associated Proteins

Amino Acids, Peptides, and Proteins > Proteins > Lectins > Lectins, C-Type > Pancreatitis-Associated Proteins

Biological Factors > Antigens > Antigens, Neoplasm > Pancreatitis-Associated Proteins

Biological Factors > Biomarkers > Biomarkers, Tumor > Pancreatitis-Associated Proteins

Pancreatitis-Associated Proteins

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C-type lectins that restrict growth of bacteria in the intestinal epithelia and have bactericidal activity against gram-positive and gram-negative bacteria. They also regulate proliferation and differentiation of KERATINOCYTES following injury. Human pancreatitis-associated protein-1 (Reg3a) is overexpressed by pancreatic ACINAR CELLS in patients with CHRONIC PANCREATITIS. It is also highly expressed by pancreatic, bladder, and gastrointestinal cancer cells and may serve as a diagnostic biomarker.

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