Concept information
Término preferido
Lymphocyte Function-Associated Antigen-1
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Tipo
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mesh:Descriptor
Definición
- An integrin heterodimer widely expressed on cells of hematopoietic origin. CD11A ANTIGEN comprises the alpha chain and the CD18 antigen (CD18 ANTIGENS) the beta chain. Lymphocyte function-associated antigen-1 is a major receptor of T-CELLS; B-CELLS; and GRANULOCYTES. It mediates the leukocyte adhesion reactions underlying cytolytic conjugate formation, helper T-cell interactions, and antibody-dependent killing by NATURAL KILLER CELLS and granulocytes. Intracellular adhesion molecule-1 has been defined as a ligand for lymphocyte function-associated antigen-1.
Concepto genérico
Etiquetas alternativas
- Integrin alphaLbeta2
- Leukocyte Function Associated Antigen-1
- LFA-1
En otras lenguas
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francés
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Antigène LFA-1
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Antigène-1 associé à la fonction des leucocytes
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Antigène-1 associé à la fonction des lymphocytes
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Antigène-1 associé à la fonction du leucocyte
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Antigène-1 associé à la fonction leucocytaire
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Antigène-1 associé à la fonction lymphocytaire
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Intégrine alpha-L-bêta-2
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Intégrine alphaLbêta2
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LFA-1(Lymphocyte function-associated antigen-1)
URI
http://data.loterre.fr/ark:/67375/JVR-PHX28MJC-K
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