Concept information
Término preferido
Factor XIIa
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Tipo
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mesh:Descriptor
Definición
- Activated form of factor XII. In the initial event in the intrinsic pathway of blood coagulation, kallikrein (with cofactor HIGH MOLECULAR WEIGHT KININOGEN) cleaves factor XII to XIIa. Factor XIIa is then further cleaved by kallikrein, plasmin, and trypsin to yield smaller factor XII fragments (Hageman-Factor fragments). These fragments increase the activity of prekallikrein to kallikrein but decrease the procoagulant activity of factor XII.
Concepto genérico
Etiquetas alternativas
- Activated Factor XII
- Blood Coagulation Factor XII, Activated
- Coagulation Factor XIIa
- Factor 12A
- Factor Twelve A
- Factor XII, Activated
- Prekallikrein Activator
En otras lenguas
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francés
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Facteur de Hageman activé
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Facteur Hageman activé
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Facteur XII activé
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Facteur XIIa de la coagulation
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Facteur XIIa de la coagulation sanguine
URI
http://data.loterre.fr/ark:/67375/JVR-PMKD9L6P-C
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