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Neuropilin-1  

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Tipo

  • mesh:Descriptor

Definición

  • A dimeric cell surface receptor involved in angiogenesis (NEOVASCULARIZATION, PHYSIOLOGICAL) and AXONAL GUIDANCE. Neuropilin-1 is a 140-kDa transmembrane protein that binds CLASS 3 SEMAPHORINS, and several other growth factors. Neuropilin-1 forms complexes with plexins or VEGF RECEPTORS; their binding affinity and specificity are determined by the composition of the neuropilin dimer and the identity of other receptors complexed with it. Neuropilin-1 is expressed in distinct patterns during neural development, complementary to those described for NEUROPILIN-2.

Concepto genérico

Etiquetas alternativas

  • 144713-63-3
  • A5 Antigen
  • Npn-1 Protein
  • NRP1 Protein
  • Sema III Receptor
  • Semaphorin III Receptor

En otras lenguas

URI

http://data.loterre.fr/ark:/67375/JVR-Q3N40KDX-4

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RDF/XML TURTLE JSON-LD Creado 3/7/02, última modificación 5/7/16