Concept information
Término preferido
Neuropilin-1
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Tipo
-
mesh:Descriptor
Definición
- A dimeric cell surface receptor involved in angiogenesis (NEOVASCULARIZATION, PHYSIOLOGICAL) and AXONAL GUIDANCE. Neuropilin-1 is a 140-kDa transmembrane protein that binds CLASS 3 SEMAPHORINS, and several other growth factors. Neuropilin-1 forms complexes with plexins or VEGF RECEPTORS; their binding affinity and specificity are determined by the composition of the neuropilin dimer and the identity of other receptors complexed with it. Neuropilin-1 is expressed in distinct patterns during neural development, complementary to those described for NEUROPILIN-2.
Concepto genérico
Etiquetas alternativas
- 144713-63-3
- A5 Antigen
- Npn-1 Protein
- NRP1 Protein
- Sema III Receptor
- Semaphorin III Receptor
En otras lenguas
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francés
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144713-63-3
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Neuropiline-1
URI
http://data.loterre.fr/ark:/67375/JVR-Q3N40KDX-4
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