: MeSH: Endothelin-1

Biological Factors > Intercellular Signaling Peptides and Proteins > Endothelins > Endothelin-1

Amino Acids, Peptides, and Proteins > Peptides > Intercellular Signaling Peptides and Proteins > Endothelins > Endothelin-1

Amino Acids, Peptides, and Proteins > Proteins > Intercellular Signaling Peptides and Proteins > Endothelins > Endothelin-1

Endothelin-1

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A 21-amino acid peptide produced in a variety of tissues including endothelial and vascular smooth-muscle cells, neurons and astrocytes in the central nervous system, and endometrial cells. It acts as a modulator of vasomotor tone, cell proliferation, and hormone production. (N Eng J Med 1995;333(6):356-63) A 38 amino acid form of endothelin-1 that results from alternative processing of proendothelin-1.

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