: MeSH: Fibrillin-1

Amino Acids, Peptides, and Proteins > Proteins > Glycoproteins > Fibrillins > Fibrillin-1

Carbohydrates > Glycoconjugates > Glycoproteins > Fibrillins > Fibrillin-1

... > Proteins > Scleroproteins > Extracellular Matrix Proteins > Fibrillins > Fibrillin-1

Fibrillin-1

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A fibrillin (FBN1) that functions as a structural support protein for MICROFIBRILS. It also regulates the maturation of OSTEOBLASTS by controlling the availability and concentration of TGF-BETA and BONE MORPHOGENETIC PROTEINS. Mutations in the FBN1 gene are associated with MARFAN SYNDROME.

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