Concept information
Amino Acids, Peptides, and Proteins
Peptides
Intracellular Signaling Peptides and Proteins
Apoptosis Regulatory Proteins
Término preferido
Apoptosis Inducing Factor
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Tipo
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mesh:Descriptor
Definición
- A flavoprotein that functions as a powerful antioxidant in the MITOCHONDRIA and promotes APOPTOSIS when released from the mitochondria. In mammalian cells AIF is released in response to pro-apoptotic protein members of the bcl-2 protein family. It translocates to the CELL NUCLEUS and binds DNA to stimulate CASPASE-independent CHROMATIN condensation.
Concepto genérico
Etiquetas alternativas
- AIF Apoptosis Regulatory Protein
- Apoptosis-Inducing Factor
- Mitochondrial Apoptosis-Inducing Factor
En otras lenguas
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francés
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AIF (Apoptosis Inducing Factor)
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Facteur AIF
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Facteur inducteur de l'apoptose
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Facteur mitochondrial inducteur d'apoptose
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Facteurs mitochondriaux inducteurs d'apoptose
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Protéine régulatrice d'apoptose AIF
URI
http://data.loterre.fr/ark:/67375/JVR-SB69MK6J-H
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