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Apoptosis Inducing Factor  

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Tipo

  • mesh:Descriptor

Definición

  • A flavoprotein that functions as a powerful antioxidant in the MITOCHONDRIA and promotes APOPTOSIS when released from the mitochondria. In mammalian cells AIF is released in response to pro-apoptotic protein members of the bcl-2 protein family. It translocates to the CELL NUCLEUS and binds DNA to stimulate CASPASE-independent CHROMATIN condensation.

Etiquetas alternativas

  • AIF Apoptosis Regulatory Protein
  • Apoptosis-Inducing Factor
  • Mitochondrial Apoptosis-Inducing Factor

En otras lenguas

  • francés

  • AIF (Apoptosis Inducing Factor)
  • Facteur AIF
  • Facteur inducteur de l'apoptose
  • Facteur mitochondrial inducteur d'apoptose
  • Facteurs mitochondriaux inducteurs d'apoptose
  • Protéine régulatrice d'apoptose AIF

URI

http://data.loterre.fr/ark:/67375/JVR-SB69MK6J-H

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