Concept information
Término preferido
Oncogene Proteins v-erbA
Notice: Undefined index: in /var/www/html/model/Concept.php on line 545
Tipo
-
mesh:Descriptor
Definición
- Transforming proteins encoded by erbA oncogenes from the avian erythroblastosis virus. They are truncated versions of c-erbA, the thyroid hormone receptor (RECEPTORS, THYROID HORMONE) that have retained both the DNA-binding and hormone-binding domains. Mutations in the hormone-binding domains abolish the transcriptional activation function. v-erbA acts as a dominant repressor of c-erbA, inducing transformation by disinhibiting proliferation.
Concepto genérico
Etiquetas alternativas
- erbA Oncogene Proteins
- Oncogene Products v-erbA
- v-erbA Proteins
En otras lenguas
-
francés
-
Produits oncogènes v-erbA
-
Protéines de l'oncogène erbA
-
Protéines v-erbA
URI
http://data.loterre.fr/ark:/67375/JVR-SCVKTDFZ-Q
{{label}}
{{#each values }} {{! loop through ConceptPropertyValue objects }}
{{#if prefLabel }}
{{/if}}
{{/each}}
{{#if notation }}{{ notation }} {{/if}}{{ prefLabel }}
{{#ifDifferentLabelLang lang }} ({{ lang }}){{/ifDifferentLabelLang}}
{{#if vocabName }}
{{ vocabName }}
{{/if}}