Skip to main

Medical Subject Headings (thesaurus)

Search from vocabulary

Concept information

Término preferido

Oncogene Proteins v-erbA  

Notice: Undefined index: in /var/www/html/model/Concept.php on line 545

Tipo

  • mesh:Descriptor

Definición

  • Transforming proteins encoded by erbA oncogenes from the avian erythroblastosis virus. They are truncated versions of c-erbA, the thyroid hormone receptor (RECEPTORS, THYROID HORMONE) that have retained both the DNA-binding and hormone-binding domains. Mutations in the hormone-binding domains abolish the transcriptional activation function. v-erbA acts as a dominant repressor of c-erbA, inducing transformation by disinhibiting proliferation.

Etiquetas alternativas

  • erbA Oncogene Proteins
  • Oncogene Products v-erbA
  • v-erbA Proteins

En otras lenguas

URI

http://data.loterre.fr/ark:/67375/JVR-SCVKTDFZ-Q

Descargue este concepto:

RDF/XML TURTLE JSON-LD Creado 23/5/94, última modificación 1/7/18