Concept information
Biological Factors
Intercellular Signaling Peptides and Proteins
Angiogenic Proteins
Angiopoietin-like Proteins
Término preferido
Angiopoietin-Like Protein 4
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Tipo
-
mesh:Descriptor
Definición
- A secreted angiopoietin-like protein expressed under hypoxic conditions by ENDOTHELIAL CELLS. It inhibits cell proliferation, cell migration, and tubule formation; the inactive form accumulates in the endothelial EXTRACELLULAR MATRIX, reducing vascular leakage. ANGPTL4 has direct roles in regulating glucose and lipid metabolism, as well as INSULIN SENSITIVITY, and may also function as a regulator of angiogenesis and tumorigenesis.
Concepto genérico
Etiquetas alternativas
- Angiopoietin-related Protein 4
- ANGPTL4 Protein
En otras lenguas
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francés
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Protéine ANGPTL4
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Protéine-4 apparentée à l'angiopoïétine
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Protéine-4 semblable à l'angiopoïétine
URI
http://data.loterre.fr/ark:/67375/JVR-SK5W2JCF-L
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