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CCCTC-Binding Factor  

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Tipo

  • mesh:Descriptor

Definición

  • A repressor protein with poly(ADP)-ribose binding activity that binds CHROMATIN and DNA; its structure consisting of 11 CYS2-HIS2 ZINC FINGERS allows it to recognize many different DNA target sites. It functions as a repressor by binding to INSULATOR ELEMENTS and preventing interaction between promoters and nearby enhancers and silencers. It plays a critical role in EPIGENETIC PROCESSES, including GENOMIC IMPRINTING.

Etiquetas alternativas

  • CTCF Protein
  • DNA-Binding Protein CTCF

En otras lenguas

  • francés

  • Facteur se fixant à la séquence CCCTC
  • Facteur se liant à la séquence CCCTC
  • Protéine CTCF
  • Protéine CTCF de liaison à l'ADN
  • Protéine CTCF se fixant à l'ADN
  • Protéine CTCF se liant à l'ADN

URI

http://data.loterre.fr/ark:/67375/JVR-SKJD27C9-T

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