Concept information
Término preferido
CCCTC-Binding Factor
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Tipo
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mesh:Descriptor
Definición
- A repressor protein with poly(ADP)-ribose binding activity that binds CHROMATIN and DNA; its structure consisting of 11 CYS2-HIS2 ZINC FINGERS allows it to recognize many different DNA target sites. It functions as a repressor by binding to INSULATOR ELEMENTS and preventing interaction between promoters and nearby enhancers and silencers. It plays a critical role in EPIGENETIC PROCESSES, including GENOMIC IMPRINTING.
Concepto genérico
Etiquetas alternativas
- CTCF Protein
- DNA-Binding Protein CTCF
En otras lenguas
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francés
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Facteur se fixant à la séquence CCCTC
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Facteur se liant à la séquence CCCTC
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Protéine CTCF
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Protéine CTCF de liaison à l'ADN
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Protéine CTCF se fixant à l'ADN
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Protéine CTCF se liant à l'ADN
URI
http://data.loterre.fr/ark:/67375/JVR-SKJD27C9-T
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