Skip to main

Medical Subject Headings (thesaurus)

Search from vocabulary

Concept information

Término preferido

Activin Receptors  

Notice: Undefined index: in /var/www/html/model/Concept.php on line 545

Tipo

  • mesh:Descriptor

Definición

  • Receptors for ACTIVINS are membrane protein kinases belonging to the family of PROTEIN-SERINE-THREONINE KINASES, thus also named activin receptor-like kinases (ALK's). Activin receptors also bind TRANSFORMING GROWTH FACTOR BETA. As those transmembrane receptors of the TGF-beta superfamily (RECEPTORS, TRANSFORMING GROWTH FACTOR BETA), ALK's consist of two different but related protein kinases, Type I and Type II. Activins initiate cellular signal transduction by first binding to the type II receptors (ACTIVIN RECEPTORS, TYPE II ) which then recruit and phosphorylate the type I receptors (ACTIVIN RECEPTORS, TYPE I ) with subsequent activation of the type I kinase activity.

Etiquetas alternativas

  • Activin Receptor
  • Activin Receptor-like Kinase
  • Activin Receptor-Like Kinases
  • Receptor, Activin

En otras lenguas

URI

http://data.loterre.fr/ark:/67375/JVR-SPK0WXFW-7

Descargue este concepto:

RDF/XML TURTLE JSON-LD Creado 25/7/01, última modificación 21/4/21