Concept information
Término preferido
Tetanus Toxin
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Tipo
-
mesh:Descriptor
Definición
- Protein synthesized by CLOSTRIDIUM TETANI as a single chain of ~150 kDa with 35% sequence identity to BOTULINUM TOXIN that is cleaved to a light and a heavy chain that are linked by a single disulfide bond. Tetanolysin is the hemolytic and tetanospasmin is the neurotoxic principle. The toxin causes disruption of the inhibitory mechanisms of the CNS, thus permitting uncontrolled nervous activity, leading to fatal CONVULSIONS.
Concepto genérico
Etiquetas alternativas
- Clostridium tetani Toxin
- Tetanus Toxins
En otras lenguas
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francés
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Toxine de Clostridium tetani
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Toxine du tétanos
URI
http://data.loterre.fr/ark:/67375/JVR-SWRP5MHF-9
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