Concept information
Término preferido
Tissue Inhibitor of Metalloproteinase-2
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Tipo
-
mesh:Descriptor
Definición
- A member of the family of TISSUE INHIBITOR OF METALLOPROTEINASES. It is a 21-kDa nonglycosylated protein found in tissue fluid and is secreted as a complex with progelatinase A by human fibroblast and uncomplexed from alveolar macrophages. An overexpression of TIMP-2 has been shown to inhibit invasive and metastatic activity of tumor cells and decrease tumor growth in vivo.
Concepto genérico
Etiquetas alternativas
- 127497-59-0
- TIMP-2
En otras lenguas
-
francés
-
127497-59-0
-
Inhibiteurs TIMP-2
-
TIMP-2
URI
http://data.loterre.fr/ark:/67375/JVR-T0JDS5TH-V
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