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WNK Lysine-Deficient Protein Kinase 1  

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Tipo

  • mesh:Descriptor

Definición

  • A serine-threonine kinase which plays an important role in the regulation of electrolyte homeostasis, cell signaling, survival, and proliferation. It functions as an activator and inhibitor of sodium-coupled chloride co-transporters and as an inhibitor of potassium-coupled chloride co-transporters. Mutations in the WNK1 gene are associated with type 2C PSEUDOHYPOALDOSTERONISM and type 2A HEREDITARY SENSORY AND AUTONOMIC NEUROPATHIES.

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URI

http://data.loterre.fr/ark:/67375/JVR-T389ZQ0Z-0

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