Concept information
Amino Acids, Peptides, and Proteins
Peptides
Intracellular Signaling Peptides and Proteins
Protein Serine-Threonine Kinases
Amino Acids, Peptides, and Proteins
Proteins
Intracellular Signaling Peptides and Proteins
Protein Serine-Threonine Kinases
Término preferido
WNK Lysine-Deficient Protein Kinase 1
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Tipo
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mesh:Descriptor
Definición
- A serine-threonine kinase which plays an important role in the regulation of electrolyte homeostasis, cell signaling, survival, and proliferation. It functions as an activator and inhibitor of sodium-coupled chloride co-transporters and as an inhibitor of potassium-coupled chloride co-transporters. Mutations in the WNK1 gene are associated with type 2C PSEUDOHYPOALDOSTERONISM and type 2A HEREDITARY SENSORY AND AUTONOMIC NEUROPATHIES.
Concepto genérico
En otras lenguas
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francés
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Protéine kinase déficiente en lysine WNK de type 1
URI
http://data.loterre.fr/ark:/67375/JVR-T389ZQ0Z-0
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