: MeSH: DNA Mismatch Repair

Chemical Phenomena > Biochemical Phenomena > DNA Repair > DNA Mismatch Repair

Genetic Phenomena > DNA Repair > DNA Mismatch Repair

DNA Mismatch Repair

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A DNA repair pathway involved in correction of errors introduced during DNA replication when an incorrect base, which cannot form hydrogen bonds with the corresponding base in the parent strand, is incorporated into the daughter strand. Excinucleases recognize the BASE PAIR MISMATCH and cause a segment of polynucleotide chain to be excised from the daughter strand, thereby removing the mismatched base. (from Oxford Dictionary of Biochemistry and Molecular Biology, 2001)

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