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... > Amino Acids, Peptides, and Proteins > Proteins > DNA-Binding Proteins > Winged-Helix Transcription Factors > Forkhead Transcription Factors > Forkhead Box Protein L2
... > Amino Acids, Peptides, and Proteins > Proteins > Transcription Factors > Winged-Helix Transcription Factors > Forkhead Transcription Factors > Forkhead Box Protein L2

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Forkhead Box Protein L2  

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Tipo

  • mesh:Descriptor

Definición

  • A forkhead box transcription factor that is expressed in the developing eyelid and during very early development of the gonad, prior to sex determination. It is essential for development of the ovary and inhibits SOX9 TRANSCRIPTION FACTOR to prevent differentiation to testes. It also induces APOPTOSIS in ovarian cells. Mutations in the FOXL2 gene are associated with BLEPHAROPHIMOSIS; Ptosis, and Epicanthus inversus (BPES with ovarian failure).

Concepto genérico

Etiquetas alternativas

  • Forkhead Box L2 Protein
  • FOXL2 Protein

En otras lenguas

URI

http://data.loterre.fr/ark:/67375/JVR-TKDWQ8ND-W

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RDF/XML TURTLE JSON-LD Creado 11/7/17, última modificación 22/5/17