Concept information
Término preferido
Superantigens
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Tipo
-
mesh:Descriptor
Definición
- Microbial antigens that have in common an extremely potent activating effect on T-cells that bear a specific variable region. Superantigens cross-link the variable region with class II MHC proteins regardless of the peptide binding in the T-cell receptor's pocket. The result is a transient expansion and subsequent death and anergy of the T-cells with the appropriate variable regions.
Concepto genérico
Conceptos específicos
Etiquetas alternativas
- Superantigen
En otras lenguas
-
francés
URI
http://data.loterre.fr/ark:/67375/JVR-TM4F44LV-T
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