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Fusion Proteins, bcr-abl  

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Tipo

  • mesh:Descriptor

Definición

  • Translation products of a fusion gene derived from CHROMOSOMAL TRANSLOCATION of C-ABL GENES to the genetic locus of the breakpoint cluster region gene on chromosome 22. Several different variants of the bcr-abl fusion proteins occur depending upon the precise location of the chromosomal breakpoint. These variants can be associated with distinct subtypes of leukemias such as PRECURSOR CELL LYMPHOBLASTIC LEUKEMIA-LYMPHOMA; LEUKEMIA, MYELOGENOUS, CHRONIC, BCR-ABL POSITIVE; and NEUTROPHILIC LEUKEMIA, CHRONIC.

Etiquetas alternativas

  • bcr-abl Fusion Protein
  • bcr-abl Fusion Proteins
  • Bcr-Abl Tyrosine Kinase

En otras lenguas

URI

http://data.loterre.fr/ark:/67375/JVR-TR708GH3-H

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