Concept information
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Peptides
Intracellular Signaling Peptides and Proteins
Protein-Tyrosine Kinases
Proto-Oncogene Proteins c-abl
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Proteins
Intracellular Signaling Peptides and Proteins
Protein-Tyrosine Kinases
Proto-Oncogene Proteins c-abl
...
Phosphotransferases (Alcohol Group Acceptor)
Protein Kinases
Protein-Tyrosine Kinases
Proto-Oncogene Proteins c-abl
...
Peptides
Intracellular Signaling Peptides and Proteins
Protein Serine-Threonine Kinases
Proto-Oncogene Proteins c-bcr
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Proteins
Intracellular Signaling Peptides and Proteins
Protein Serine-Threonine Kinases
Proto-Oncogene Proteins c-bcr
...
Phosphotransferases (Alcohol Group Acceptor)
Protein Kinases
Protein Serine-Threonine Kinases
Proto-Oncogene Proteins c-bcr
Término preferido
Fusion Proteins, bcr-abl
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Tipo
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mesh:Descriptor
Definición
- Translation products of a fusion gene derived from CHROMOSOMAL TRANSLOCATION of C-ABL GENES to the genetic locus of the breakpoint cluster region gene on chromosome 22. Several different variants of the bcr-abl fusion proteins occur depending upon the precise location of the chromosomal breakpoint. These variants can be associated with distinct subtypes of leukemias such as PRECURSOR CELL LYMPHOBLASTIC LEUKEMIA-LYMPHOMA; LEUKEMIA, MYELOGENOUS, CHRONIC, BCR-ABL POSITIVE; and NEUTROPHILIC LEUKEMIA, CHRONIC.
Concepto genérico
Etiquetas alternativas
- bcr-abl Fusion Protein
- bcr-abl Fusion Proteins
- Bcr-Abl Tyrosine Kinase
En otras lenguas
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francés
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Tyrosine kinase bcr-abl
URI
http://data.loterre.fr/ark:/67375/JVR-TR708GH3-H
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