Concept information
Immune System Diseases
Autoimmune Diseases
Autoimmune Diseases of the Nervous System
Demyelinating Autoimmune Diseases, CNS
Término preferido
Multiple Sclerosis
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Tipo
-
mesh:Descriptor
Definición
- An autoimmune disorder mainly affecting young adults and characterized by destruction of myelin in the central nervous system. Pathologic findings include multiple sharply demarcated areas of demyelination throughout the white matter of the central nervous system. Clinical manifestations include visual loss, extra-ocular movement disorders, paresthesias, loss of sensation, weakness, dysarthria, spasticity, ataxia, and bladder dysfunction. The usual pattern is one of recurrent attacks followed by partial recovery (see MULTIPLE SCLEROSIS, RELAPSING-REMITTING), but acute fulminating and chronic progressive forms (see MULTIPLE SCLEROSIS, CHRONIC PROGRESSIVE) also occur. (Adams et al., Principles of Neurology, 6th ed, p903)
Concepto genérico
Conceptos específicos
Etiquetas alternativas
- MS (Multiple Sclerosis)
- Sclerosis, Disseminated
En otras lenguas
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francés
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Sclérose disséminée
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SEP (Sclérose En Plaques)
URI
http://data.loterre.fr/ark:/67375/JVR-V1248ZXJ-L
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