Concept information
Término preferido
Integrin alphaVbeta3
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Tipo
-
mesh:Descriptor
Definición
- An integrin that binds to a variety of plasma and extracellular matrix proteins containing the conserved RGD amino acid sequence and modulates cell adhesion. Integrin alphavbeta3 is highly expressed in OSTEOCLASTS where it may play role in BONE RESORPTION. It is also abundant in vascular smooth muscle and endothelial cells, and in some tumor cells, where it is involved in angiogenesis and cell migration. Although often referred to as the vitronectin receptor there is more than one receptor for vitronectin (RECEPTORS, VITRONECTIN).
Concepto genérico
Etiquetas alternativas
- alpha-v beta-3 Integrin Receptors
- Integrin alpha-v beta-3
- Receptors, alpha-v beta-3 Integrin
- Vitronectin Receptor
En otras lenguas
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francés
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Intégrine alpha-V-bêta-3
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Intégrine alphaV bêta3
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Récepteur de la vitronectine
URI
http://data.loterre.fr/ark:/67375/JVR-V7W6RV9F-F
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