Concept information
Término preferido
Promyelocytic Leukemia Zinc Finger Protein
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Tipo
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mesh:Descriptor
Definición
- A Kruppel-type transcription factor consisting of an N-terminal BTB DOMAIN and nine CYS2-HIS2 ZINC FINGERS. It localizes to the nucleus and regulates cell cycle progression and gene expression for tissue development and homeostasis; it may also function as an epigenetic regulator through its interactions with HISTONE DEACETYLASE. Genetic rearrangements involving the ZBTB16 gene are associated with ACUTE PROMYELOCYTIC LEUKEMIA.
Concepto genérico
Etiquetas alternativas
- PLZF Protein
- Promyelocytic Leukaemia Zinc Finger Protein
- ZBTB16 Protein
- Zinc Finger and BTB Domain Containing 16 Protein
En otras lenguas
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francés
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Protéine à doigt de zinc de la leucémie promyélocytaire
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Protéine PLZF
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Protéine ZBTB16
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Protéine-16 contenant des doigts de zinc et un domains BTB
URI
http://data.loterre.fr/ark:/67375/JVR-VKZ967WZ-J
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