Concept information
Término preferido
Mad2 Proteins
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Tipo
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mesh:Descriptor
Definición
- Mad2 is a component of the spindle-assembly checkpoint apparatus. It binds to and inhibits the Cdc20 activator subunit of the anaphase-promoting complex, preventing the onset of anaphase until all chromosomes are properly aligned at the metaphase plate. Mad2 is required for proper microtubule capture at KINETOCHORES.
Concepto genérico
Etiquetas alternativas
- Mad2 Mitotic Arrest Deficient-like 1 Proteins
En otras lenguas
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francés
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Mad2 Mitotic arrest deficient-like 1 proteins
URI
http://data.loterre.fr/ark:/67375/JVR-WRBZMQ0R-0
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