: MeSH: Multiple Endocrine Neoplasia Type 2a

Congenital, Hereditary, and Neonatal Diseases and Abnormalities > Genetic Diseases, Inborn > Neoplastic Syndromes, Hereditary > Multiple Endocrine Neoplasia > Multiple Endocrine Neoplasia Type 2a

Neoplasms > Neoplastic Syndromes, Hereditary > Multiple Endocrine Neoplasia > Multiple Endocrine Neoplasia Type 2a

Endocrine System Diseases > Endocrine Gland Neoplasms > Multiple Endocrine Neoplasia > Multiple Endocrine Neoplasia Type 2a

Neoplasms > Neoplasms by Site > Endocrine Gland Neoplasms > Multiple Endocrine Neoplasia > Multiple Endocrine Neoplasia Type 2a

Neoplasms > Neoplasms, Multiple Primary > Multiple Endocrine Neoplasia > Multiple Endocrine Neoplasia Type 2a

Multiple Endocrine Neoplasia Type 2a

Notice: Undefined index: in /var/www/html/model/Concept.php on line 545

A form of multiple endocrine neoplasia characterized by the presence of medullary carcinoma (CARCINOMA, MEDULLARY) of the THYROID GLAND, and usually with the co-occurrence of PHEOCHROMOCYTOMA, producing CALCITONIN and ADRENALINE, respectively. Less frequently, it can occur with hyperplasia or adenoma of the PARATHYROID GLANDS. This disease is due to gain-of-function mutations of the MEN2 gene on CHROMOSOME 10 (Locus: 10q11.2), also known as the RET proto-oncogene that encodes a RECEPTOR PROTEIN-TYROSINE KINASE. It is an autosomal dominant inherited disease.

http://data.loterre.fr/ark:/67375/JVR-WS3K33VK-R

RDF/XML TURTLE JSON-LD Creado 23/5/94, última modificación 3/7/12

Loterre