: MeSH: Proliferating Cell Nuclear Antigen

Biological Factors > Biomarkers > Biomarkers, Tumor > Proliferating Cell Nuclear Antigen

Amino Acids, Peptides, and Proteins > Proteins > Nuclear Proteins > Antigens, Nuclear > Proliferating Cell Nuclear Antigen

Biological Factors > Antigens > Antigens, Nuclear > Proliferating Cell Nuclear Antigen

Proliferating Cell Nuclear Antigen

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Nuclear antigen with a role in DNA synthesis, DNA repair, and cell cycle progression. PCNA is required for the coordinated synthesis of both leading and lagging strands at the replication fork during DNA replication. PCNA expression correlates with the proliferation activity of several malignant and non-malignant cell types.

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