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Integrin alpha Chains  

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Tipo

  • mesh:Descriptor

Definición

  • The alpha subunits of integrin heterodimers (INTEGRINS), which mediate ligand specificity. There are approximately 18 different alpha chains, exhibiting great sequence diversity; several chains are also spliced into alternative isoforms. They possess a long extracellular portion (1200 amino acids) containing a MIDAS (metal ion-dependent adhesion site) motif, and seven 60-amino acid tandem repeats, the last 4 of which form EF HAND MOTIFS. The intracellular portion is short with the exception of INTEGRIN ALPHA4.

Concepto genérico

Etiquetas alternativas

  • alpha Integrins
  • Integrin alpha Subunits

En otras lenguas

  • francés

  • Chaines alpha des intégrines
  • Chaînes alpha des intégrines
  • Sous-unités alpha des intégrines

URI

http://data.loterre.fr/ark:/67375/JVR-X5X803P5-Z

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