Concept information
Término preferido
Integrin alpha Chains
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Tipo
-
mesh:Descriptor
Definición
- The alpha subunits of integrin heterodimers (INTEGRINS), which mediate ligand specificity. There are approximately 18 different alpha chains, exhibiting great sequence diversity; several chains are also spliced into alternative isoforms. They possess a long extracellular portion (1200 amino acids) containing a MIDAS (metal ion-dependent adhesion site) motif, and seven 60-amino acid tandem repeats, the last 4 of which form EF HAND MOTIFS. The intracellular portion is short with the exception of INTEGRIN ALPHA4.
Concepto genérico
Conceptos específicos
Etiquetas alternativas
- alpha Integrins
- Integrin alpha Subunits
En otras lenguas
-
francés
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Chaines alpha des intégrines
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Chaînes alpha des intégrines
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Sous-unités alpha des intégrines
URI
http://data.loterre.fr/ark:/67375/JVR-X5X803P5-Z
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