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Transcription Factor 4  

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Tipo

  • mesh:Descriptor

Definición

  • A basic helix-loop-helix leucine zipper transcription factor that functions in neuronal CELL DIFFERENTIATION. It dimerizes with other bHLH transcription factors and activates transcription through binding to E-BOX ELEMENTS containing 5'-ACANNTGT-3' or 5'-CCANNTGG-3' sequences. Mutations in the TCF-4 gene are associated with Pitt-Hopkins Syndrome, a severe developmental disorder.

Etiquetas alternativas

  • TCF-4 Protein
  • TCF-4 Transcription Factor
  • TCF4 Transcription Factor

En otras lenguas

  • francés

  • Facteur de transcription TCF-4
  • Facteur de transcription TCF4
  • Facteur transcriptionnel TCF-4
  • Facteur transcriptionnel TCF4
  • Facteur transcriptionnel-4
  • Protéine TCF-4

URI

http://data.loterre.fr/ark:/67375/JVR-XFN61GND-F

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