Concept information
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Proteins
DNA-Binding Proteins
Basic Helix-Loop-Helix Transcription Factors
Basic Helix-Loop-Helix Leucine Zipper Transcription Factors
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Proteins
Transcription Factors
Basic Helix-Loop-Helix Transcription Factors
Basic Helix-Loop-Helix Leucine Zipper Transcription Factors
Término preferido
Transcription Factor 4
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Tipo
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mesh:Descriptor
Definición
- A basic helix-loop-helix leucine zipper transcription factor that functions in neuronal CELL DIFFERENTIATION. It dimerizes with other bHLH transcription factors and activates transcription through binding to E-BOX ELEMENTS containing 5'-ACANNTGT-3' or 5'-CCANNTGG-3' sequences. Mutations in the TCF-4 gene are associated with Pitt-Hopkins Syndrome, a severe developmental disorder.
Concepto genérico
Etiquetas alternativas
- TCF-4 Protein
- TCF-4 Transcription Factor
- TCF4 Transcription Factor
En otras lenguas
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francés
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Facteur de transcription TCF-4
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Facteur de transcription TCF4
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Facteur transcriptionnel TCF-4
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Facteur transcriptionnel TCF4
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Facteur transcriptionnel-4
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Protéine TCF-4
URI
http://data.loterre.fr/ark:/67375/JVR-XFN61GND-F
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