Concept information
Término preferido
Immunoglobulin Class Switching
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Tipo
-
mesh:Descriptor
Definición
- Gene rearrangement of the B-lymphocyte which results in a substitution in the type of heavy-chain constant region that is expressed. This allows the effector response to change while the antigen binding specificity (variable region) remains the same. The majority of class switching occurs by a DNA recombination event but it also can take place at the level of RNA processing.
Concepto genérico
Etiquetas alternativas
- Class Switching
- Ig Class Switching
- Isotype Switching
En otras lenguas
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francés
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Commutation d'isotype
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Commutation de classe
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Commutation de classe des Ig
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Commutation isotypique
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Commutation isotypique des Ig
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Commutation isotypique des immunoglobulines
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Switch isotypique
URI
http://data.loterre.fr/ark:/67375/JVR-XKXHNXDL-D
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