Concept information
Término preferido
Tetrahydrofolate Dehydrogenase
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Tipo
-
mesh:Descriptor
Definición
- An enzyme of the oxidoreductase class that catalyzes the reaction 7,8-dihyrofolate and NADPH to yield 5,6,7,8-tetrahydrofolate and NADPH+, producing reduced folate for amino acid metabolism, purine ring synthesis, and the formation of deoxythymidine monophosphate. Methotrexate and other folic acid antagonists used as chemotherapeutic drugs act by inhibiting this enzyme. (Dorland, 27th ed) EC 1.5.1.3.
Concepto genérico
Etiquetas alternativas
- 5,6,7,8-Tetrahydrofolate:NADP+ oxidoreductase
- Dihydrofolate Dehydrogenase
- Dihydrofolate Reductase
- Folic Acid Reductase
En otras lenguas
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francés
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5,6,7,8-Tetrahydrofolate:NADP+ oxidoreductase
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Dihydrofolate déshydrogénase
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Tétrahydrofolate déshydrogénase
URI
http://data.loterre.fr/ark:/67375/JVR-Z9XMXKG3-1
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