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Amino Acids, Peptides, and Proteins > Peptides > Intracellular Signaling Peptides and Proteins > Sirtuins
Amino Acids, Peptides, and Proteins > Proteins > Intracellular Signaling Peptides and Proteins > Sirtuins
... > Enzymes and Coenzymes > Enzymes > Transferases > Glycosyltransferases > Pentosyltransferases > ADP Ribose Transferases > Sirtuins
... > Enzymes and Coenzymes > Enzymes > Hydrolases > Amidohydrolases > Histone Deacetylases > Group III Histone Deacetylases > Sirtuins

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Sirtuins  

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Tipo

  • mesh:Descriptor

Definición

  • A homologous family of regulatory enzymes that are structurally related to the protein silent mating type information regulator 2 (Sir2) found in Saccharomyces cerevisiae. Sirtuins contain a central catalytic core region which binds NAD. Several of the sirtuins utilize NAD to deacetylate proteins such as HISTONES and are categorized as GROUP III HISTONE DEACETYLASES. Several other sirtuin members utilize NAD to transfer ADP-RIBOSE to proteins and are categorized as MONO ADP-RIBOSE TRANSFERASES, while a third group of sirtuins appears to have both deacetylase and ADP ribose transferase activities.

Concepto genérico

Conceptos específicos

Conceptos relacionados

Etiquetas alternativas

  • Silent Mating Type Information Regulator 2-like Proteins
  • Sir2-like Proteins
  • SIRT
  • SIRTs
  • Sirtuin

En otras lenguas

  • Sirtuines

    francés

  • Protéines Sir2-like
  • SIRT

URI

http://data.loterre.fr/ark:/67375/JVR-ZN52ZLS2-M

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RDF/XML TURTLE JSON-LD Creado 3/7/02, última modificación 27/5/20