Concept information
Término preferido
Mucosa-Associated Lymphoid Tissue Lymphoma Translocation 1 Protein
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Tipo
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mesh:Descriptor
Definición
- A caspase-like cysteine endopeptidase that also exhibits ubiquitin ligase activity. It contains an N-terminal DEATH DOMAIN, two IMMUNOGLOBULIN-LIKE DOMAINS, and localizes to the perinuclear region of MONOCYTES, where it functions in activation of NF-KAPPA B; it also binds to and activates TRAF6. Chromosomal translocations involving the MALT1 and BIRC2 genes are associated with MALT LYMPHOMA, and mutations in the MALT1 gene are associated with Type 12 IMMUNODEFICIENCY SYNDROMES.
Concepto genérico
Etiquetas alternativas
- MALT1 Paracaspase
- MALT-1 Protein
- MALT1 Protein
- Paracaspase
En otras lenguas
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francés
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Paracaspase
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Paracaspase MALT1
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Protéine MALT-1
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Protéine MALT1
URI
http://data.loterre.fr/ark:/67375/JVR-ZP60TN2N-X
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