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Complement C5a  

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Tipo

  • mesh:Descriptor

Definición

  • The minor fragment formed when C5 convertase cleaves C5 into C5a and COMPLEMENT C5B. C5a is a 74-amino-acid glycopeptide with a carboxy-terminal ARGININE that is crucial for its spasmogenic activity. Of all the complement-derived anaphylatoxins, C5a is the most potent in mediating immediate hypersensitivity (HYPERSENSITIVITY, IMMEDIATE), smooth MUSCLE CONTRACTION; HISTAMINE RELEASE; and migration of LEUKOCYTES to site of INFLAMMATION.

Concepto genérico

Conceptos específicos

Etiquetas alternativas

  • 80295-54-1
  • C5a Complement
  • Complement 5a
  • Complement Component 5a

En otras lenguas

  • francés

  • 80295-54-1
  • Complement C5a
  • Composant C5a du complément
  • Fraction C5a du complément
  • Fragment C5a du complément

URI

http://data.loterre.fr/ark:/67375/JVR-ZPZCDMQ7-J

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