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Amino Acids, Peptides, and Proteins > Peptides > Intracellular Signaling Peptides and Proteins > Apoptosis Regulatory Proteins > High-Temperature Requirement A Serine Peptidase 2
Amino Acids, Peptides, and Proteins > Proteins > Intracellular Signaling Peptides and Proteins > Apoptosis Regulatory Proteins > High-Temperature Requirement A Serine Peptidase 2
Amino Acids, Peptides, and Proteins > Proteins > Mitochondrial Proteins > High-Temperature Requirement A Serine Peptidase 2
... > Enzymes and Coenzymes > Enzymes > Hydrolases > Peptide Hydrolases > Serine Proteases > Serine Endopeptidases > High-Temperature Requirement A Serine Peptidase 2
... > Enzymes and Coenzymes > Enzymes > Hydrolases > Peptide Hydrolases > Endopeptidases > Serine Endopeptidases > High-Temperature Requirement A Serine Peptidase 2
Amino Acids, Peptides, and Proteins > Proteins > Parkinson Disease Associated Proteins > High-Temperature Requirement A Serine Peptidase 2

Término preferido

High-Temperature Requirement A Serine Peptidase 2  

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Tipo

  • mesh:Descriptor

Definición

  • A serine peptidase that contains a C-terminal PDZ domain. It localizes to the mitochondrial membrane and intermembrane space, translocating to the cytoplasm following APOPTOSIS stimuli, such as UV irradiation; it promotes cell death by binding to and inhibiting INHIBITOR OF APOPTOSIS PROTEINS, resulting in an increase in activity of CASPASES. Mutations in the HTRA2 gene are associated with Type 13 PARKINSON DISEASE.

Concepto genérico

Conceptos relacionados

Etiquetas alternativas

  • HtrA Serine Peptidase 2
  • HtrA2 Protease
  • Omi Serine Protease
  • Serine Protease HTRA2
  • Serine Protease Omi

En otras lenguas

  • High-temperature requirement A serine peptidase 2

    francés

  • Protéase HTRA2
  • Sérine peptidase A2 requise à haute température
  • Sérine peptidase A2 requise à température élevée
  • Sérine peptidase HtrA2
  • Sérine protéase A2 requise à haute température
  • Sérine protéase A2 requise à température élevée
  • Serine protease HTRA2
  • Sérine protéase HTRA2
  • Sérine protéase Omi
  • Sérine protéinase A2 requise à haute température

URI

http://data.loterre.fr/ark:/67375/JVR-ZTRXT0MG-0

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RDF/XML TURTLE JSON-LD Creado 11/7/17, última modificación 28/6/21