Concept information
Término preferido
NLR Family, Pyrin Domain-Containing 3 Protein
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Tipo
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mesh:Descriptor
Definición
- An NLR protein that contains an N-terminal PYRIN DOMAIN and ATP-binding site and 9 C-terminal LEUCINE-rich repeats; it is expressed primarily by MACROPHAGES. It is a core component of the INFLAMMASOME and directs its assembly in response to pathogen infection and damage-associated stimuli. Mutations in the NLRP3 gene are associated with FAMILIAL COLD AUTOINFLAMMATORY SYNDROME.
Concepto genérico
Etiquetas alternativas
- Cold Autoinflammatory Syndrome 1 Protein
- NACHT, LRR and PYD Domains-Containing Protein 3
- NLRP3 Protein
En otras lenguas
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francés
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Protéine NLRP3
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Protéine-1 de l'urticaire familial au froid
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Protéine-1 du syndrome familial auto-inflammatoire au froid
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Protéine-3 contenant des domaines NACHT, LRR et PYD
URI
http://data.loterre.fr/ark:/67375/JVR-ZZ2T5CN0-4
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