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Concept information

Biological Factors > Intercellular Signaling Peptides and Proteins > Agouti Signaling Protein
Amino Acids, Peptides, and Proteins > Peptides > Intercellular Signaling Peptides and Proteins > Agouti Signaling Protein
Amino Acids, Peptides, and Proteins > Proteins > Intercellular Signaling Peptides and Proteins > Agouti Signaling Protein

Terme préférentiel

Agouti Signaling Protein  

Type

  • mesh:Descriptor

Définition

  • A secreted protein of approximately 131 amino acids (depending on species) that regulates the synthesis of eumelanin (brown/black) pigments in MELANOCYTES. Agouti protein antagonizes the signaling of MELANOCORTIN RECEPTORS and has wide distribution including ADIPOSE TISSUE; GONADS; and HEART. Its overexpression in agouti mice results in uniform yellow coat color, OBESITY, and metabolic defects similar to type II diabetes in humans.

Concept générique

Synonyme(s)

  • Agouti Protein
  • Agouti Switch Protein
  • ASIP Protein

Qualificatif(s) autorisé(s)

Traductions

URI

http://data.loterre.fr/ark:/67375/JVR-B98RW6CQ-X

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RDF/XML TURTLE JSON-LD Date de création 09/07/2007