Concept information
Terme préférentiel
Baclofen
Type
-
mesh:Descriptor
Définition
- A GAMMA-AMINOBUTYRIC ACID derivative that is a specific agonist of GABA-B RECEPTORS. It is used in the treatment of MUSCLE SPASTICITY, especially that due to SPINAL CORD INJURIES. Its therapeutic effects result from actions at spinal and supraspinal sites, generally the reduction of excitatory transmission.
Concept générique
Synonyme(s)
- 1134-47-0 (Baclofen)
- Baclophen
- Benzenepropanoic acid, beta-(aminomethyl)-4-chloro-
- beta-(Aminomethyl)-4-chlorobenzenepropanoic Acid
- beta-(p-Chlorophenyl)-gamma-aminobutyric Acid
- Chlorophenyl GABA
- H789N3FKE8
- PCP-GABA
Qualificatif(s) autorisé(s)
- administration & dosage (Qualifier)
- adverse effects (Qualifier)
- agonists (Qualifier)
- analogs & derivatives (Qualifier)
- analysis (Qualifier)
- antagonists & inhibitors (Qualifier)
- blood (Qualifier)
- cerebrospinal fluid (Qualifier)
- chemical synthesis (Qualifier)
- chemistry (Qualifier)
- classification (Qualifier)
- economics (Qualifier)
- history (Qualifier)
- immunology (Qualifier)
- isolation & purification (Qualifier)
- metabolism (Qualifier)
- pharmacokinetics (Qualifier)
- pharmacology (Qualifier)
- poisoning (Qualifier)
- radiation effects (Qualifier)
- standards (Qualifier)
- supply & distribution (Qualifier)
- therapeutic use (Qualifier)
- toxicity (Qualifier)
- urine (Qualifier)
Action(s) pharmacologique(s)
Traductions
-
français
-
1134-47-0 (Baclofen)
-
Benzenepropanoic acid, beta-(aminomethyl)-4-chloro-
-
bêta-4-chlorophényl-GABA
-
H789N3FKE8
-
PCP-GABA
URI
http://data.loterre.fr/ark:/67375/JVR-BKMFQ6DG-H
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