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Concept information

Cell Physiological Phenomena > Cellular Senescence > Senescence-Associated Secretory Phenotype
Physiological Phenomena > Growth and Development > Aging > Cellular Senescence > Senescence-Associated Secretory Phenotype

Terme préférentiel

Senescence-Associated Secretory Phenotype  

Type

  • mesh:Descriptor

Définition

  • A paracrine pro-inflammatory phenotype developed in senescing cells. The senescence-associated secretory phenotype (SASP) results from the inflammatory, proteolytic and growth factor enriched SECRETOME of many types of senescent cells which leads to tissue repair or tissue and organ damage over time and links SASP to age-related disorders.

Concept générique

Synonyme(s)

  • Senescent Cell SASP

Qualificatif(s) autorisé(s)

Traductions

URI

http://data.loterre.fr/ark:/67375/JVR-BSLD20NF-S

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RDF/XML TURTLE JSON-LD Date de création 09/07/2021, dernière modification le 07/07/2021