Concept information
Terme préférentiel
Methotrexate
Type
-
mesh:Descriptor
Définition
- An antineoplastic antimetabolite with immunosuppressant properties. It is an inhibitor of TETRAHYDROFOLATE DEHYDROGENASE and prevents the formation of tetrahydrofolate, necessary for synthesis of thymidylate, an essential component of DNA.
Concept générique
Synonyme(s)
- 133073-73-1 (x.H2O)
- 15475-56-6 (Na salt)
- 3IG1E710ZN
- 51865-79-3 ((D)-isomer)
- 59-05-2 (Methotrexate)
- 60388-53-6 ((DL)-isomer)
- 86669-44-5 (di-Cs salt)
- Amethopterin
- L-Glutamic acid, N-(4-(((2,4-diamino-6-pteridinyl)methyl)methylamino)benzoyl)-
- YL5FZ2Y5U1
Qualificatif(s) autorisé(s)
- administration & dosage (Qualifier)
- adverse effects (Qualifier)
- agonists (Qualifier)
- analogs & derivatives (Qualifier)
- analysis (Qualifier)
- antagonists & inhibitors (Qualifier)
- blood (Qualifier)
- cerebrospinal fluid (Qualifier)
- chemical synthesis (Qualifier)
- chemistry (Qualifier)
- classification (Qualifier)
- economics (Qualifier)
- history (Qualifier)
- immunology (Qualifier)
- isolation & purification (Qualifier)
- metabolism (Qualifier)
- pharmacokinetics (Qualifier)
- pharmacology (Qualifier)
- poisoning (Qualifier)
- radiation effects (Qualifier)
- standards (Qualifier)
- supply & distribution (Qualifier)
- therapeutic use (Qualifier)
- toxicity (Qualifier)
- urine (Qualifier)
Action(s) pharmacologique(s)
Traductions
-
français
-
133073-73-1 (x.H2O)
-
15475-56-6 (Na salt)
-
3IG1E710ZN
-
51865-79-3 ((D)-isomer)
-
59-05-2 (Methotrexate)
-
60388-53-6 ((DL)-isomer)
-
86669-44-5 (di-Cs salt)
-
Améthoptérine
-
L-Glutamic acid, N-(4-(((2,4-diamino-6-pteridinyl)methyl)methylamino)benzoyl)-
-
Méthylaminoptérine
-
YL5FZ2Y5U1
URI
http://data.loterre.fr/ark:/67375/JVR-C27LRJKB-8
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