Concept information
Terme préférentiel
DEAD Box Protein 58
Type
-
mesh:Descriptor
Définition
- A DEAD-box RNA helicase that contains an N-terminal DEATH-LIKE DOMAIN, AAA+ ATPase domain, and C-terminal RNA HELICASE activity. It functions as an innate immune receptor through its recognition of viral nucleic acids. It also induces the expression of INTERFERON TYPE I and proinflammatory CYTOKINES. Its ligands include: 5'-triphosphorylated SINGLE-STRANDED RNA, DOUBLE-STRANDED RNA (dsRNA), and short dsRNA (less than 1 kb in length).
Concept générique
Synonyme(s)
- DEAD (Asp-Glu-Ala-Asp) Box Polypeptide 58
- Probable ATP-Dependent RNA Helicase DDX58
- RIG-I-like Receptor 1
Qualificatif(s) autorisé(s)
- administration & dosage (Qualifier)
- adverse effects (Qualifier)
- analysis (Qualifier)
- antagonists & inhibitors (Qualifier)
- biosynthesis (Qualifier)
- blood (Qualifier)
- cerebrospinal fluid (Qualifier)
- chemical synthesis (Qualifier)
- chemistry (Qualifier)
- classification (Qualifier)
- deficiency (Qualifier)
- drug effects (Qualifier)
- economics (Qualifier)
- genetics (Qualifier)
- history (Qualifier)
- immunology (Qualifier)
- isolation & purification (Qualifier)
- metabolism (Qualifier)
- pharmacokinetics (Qualifier)
- pharmacology (Qualifier)
- physiology (Qualifier)
- poisoning (Qualifier)
- radiation effects (Qualifier)
- standards (Qualifier)
- supply & distribution (Qualifier)
- therapeutic use (Qualifier)
- toxicity (Qualifier)
- ultrastructure (Qualifier)
- urine (Qualifier)
Traductions
-
français
-
Hélicase à ARN putative DDX58
-
Polypeptide-58 à domaine DEAD (Asp-Glu-Ala-Asp)
-
Probable ATP-dependent RNA helicase DDX58
-
Récepteur-1 semblable à RIG-I
-
Récepteur-1 similaire à RIG-I
URI
http://data.loterre.fr/ark:/67375/JVR-C62WS52T-P
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