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Concept information

... > Lipids > Fatty Acids > Fatty Acids, Unsaturated > Eicosanoids > Arachidonic Acids > Leukotrienes > Leukotriene A4
... > Biological Factors > Inflammation Mediators > Autacoids > Eicosanoids > Arachidonic Acids > Leukotrienes > Leukotriene A4
... > Lipids > Fatty Acids > Fatty Acids, Unsaturated > Fatty Acids, Essential > Arachidonic Acids > Leukotrienes > Leukotriene A4

Terme préférentiel

Leukotriene A4  

Type

  • mesh:Descriptor

Définition

  • (2S-(2 alpha,3 beta(1E,3E,5Z,8Z)))-3-(1,3,5,8-Tetradecatetraenyl)oxiranebutanoic acid. An unstable allylic epoxide, formed from the immediate precursor 5-HPETE via the stereospecific removal of a proton at C-10 and dehydration. Its biological actions are determined primarily by its metabolites, i.e., LEUKOTRIENE B4 and cysteinyl-leukotrienes. Alternatively, leukotriene A4 is converted into LEUKOTRIENE C4 by glutathione-S-transferase or into 5,6-di-HETE by the epoxide-hydrolase. (From Dictionary of Prostaglandins and Related Compounds, 1990)

Concept générique

Synonyme(s)

  • Leukotriene A-4
  • LTA4

Qualificatif(s) autorisé(s)

Traductions

URI

http://data.loterre.fr/ark:/67375/JVR-C807BTHQ-V

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RDF/XML TURTLE JSON-LD Date de création 04/06/1993, dernière modification le 08/06/2015