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Concept information

Biological Factors > Blood Coagulation Factors > Plasminogen Activators > Tissue Plasminogen Activator
... > Amino Acids, Peptides, and Proteins > Proteins > Blood Proteins > Blood Coagulation Factors > Plasminogen Activators > Tissue Plasminogen Activator
... > Enzymes and Coenzymes > Enzymes > Hydrolases > Peptide Hydrolases > Serine Proteases > Serine Endopeptidases > Plasminogen Activators > Tissue Plasminogen Activator
... > Enzymes and Coenzymes > Enzymes > Hydrolases > Peptide Hydrolases > Endopeptidases > Serine Endopeptidases > Plasminogen Activators > Tissue Plasminogen Activator

Terme préférentiel

Tissue Plasminogen Activator  

Type

  • mesh:Descriptor

Définition

  • A proteolytic enzyme in the serine protease family found in many tissues which converts PLASMINOGEN to FIBRINOLYSIN. It has fibrin-binding activity and is immunologically different from UROKINASE-TYPE PLASMINOGEN ACTIVATOR. The primary sequence, composed of 527 amino acids, is identical in both the naturally occurring and synthetic proteases.

Concept générique

Concepts spécifiques

Synonyme(s)

  • 105857-23-6 (Alteplase)
  • Alteplase
  • Plasminogen Activator, Tissue-Type
  • Tisokinase
  • Tissue Activator D-44
  • Tissue-Type Plasminogen Activator
  • T-Plasminogen Activator
  • TTPA

Qualificatif(s) autorisé(s)

Action(s) pharmacologique(s)

Traductions

URI

http://data.loterre.fr/ark:/67375/JVR-C8BHCSFT-7

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RDF/XML TURTLE JSON-LD Date de création 12/06/1985, dernière modification le 01/07/2016