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Inorganic Chemicals > Sulfur Compounds > Thiazoles > Thiadiazoles > Acetazolamide

Organic Chemicals > Sulfur Compounds > Thiazoles > Thiadiazoles > Acetazolamide

... > Heterocyclic Compounds, 1-Ring > Azoles > Thiazoles > Thiadiazoles > Acetazolamide

Terme préférentiel

Acetazolamide

mesh:Descriptor

One of the CARBONIC ANHYDRASE INHIBITORS that is sometimes effective against absence seizures. It is sometimes useful also as an adjunct in the treatment of tonic-clonic, myoclonic, and atonic seizures, particularly in women whose seizures occur or are exacerbated at specific times in the menstrual cycle. However, its usefulness is transient often because of rapid development of tolerance. Its antiepileptic effect may be due to its inhibitory effect on brain carbonic anhydrase, which leads to an increased transneuronal chloride gradient, increased chloride current, and increased inhibition. (From Smith and Reynard, Textbook of Pharmacology, 1991, p337)

Thiadiazoles

1424-27-7 (mono-Na salt)
59-66-5 (Acetazolamide)
Acetamide, N-(5-(aminosulfonyl)-1,3,4-thiadiazol-2-yl)-
O3FX965V0I

Qualificatif(s) autorisé(s)

Action(s) pharmacologique(s)

Acétazolamide

français
1424-27-7 (mono-Na salt)
59-66-5 (Acetazolamide)
Acetamide, N-(5-(aminosulfonyl)-1,3,4-thiadiazol-2-yl)-
O3FX965V0I

URI

http://data.loterre.fr/ark:/67375/JVR-CQQB7N39-M

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RDF/XML TURTLE JSON-LD Date de création 01/01/1999, dernière modification le 24/06/2016