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Concept information

Genetic Phenomena > Gene Expression Regulation > Epigenesis, Genetic > Dosage Compensation, Genetic

Terme préférentiel

Dosage Compensation, Genetic  

Type

  • mesh:Descriptor

Définition

  • Genetic mechanisms that allow GENES to be expressed at a similar level irrespective of their GENE DOSAGE. This term is usually used in discussing genes that lie on the SEX CHROMOSOMES. Because the sex chromosomes are only partially homologous, there is a different copy number, i.e., dosage, of these genes in males vs. females. In DROSOPHILA, dosage compensation is accomplished by hypertranscription of genes located on the X CHROMOSOME. In mammals, dosage compensation of X chromosome genes is accomplished by random X CHROMOSOME INACTIVATION of one of the two X chromosomes in the female.

Concept générique

Concepts spécifiques

Synonyme(s)

  • Dosage Compensation (Genetics)
  • Gene Dosage Compensation

Qualificatif(s) autorisé(s)

Traductions

URI

http://data.loterre.fr/ark:/67375/JVR-DHT89QVG-N

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RDF/XML TURTLE JSON-LD Date de création 23/02/1981, dernière modification le 17/06/2016