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Concept information

... > Amino Acids, Peptides, and Proteins > Proteins > Blood Proteins > Acute-Phase Proteins > Fibrinogen > Fibrinogens, Abnormal
Biological Factors > Blood Coagulation Factors > Fibrinogen > Fibrinogens, Abnormal
... > Amino Acids, Peptides, and Proteins > Proteins > Blood Proteins > Blood Coagulation Factors > Fibrinogen > Fibrinogens, Abnormal
Amino Acids, Peptides, and Proteins > Proteins > Protein Precursors > Fibrinogen > Fibrinogens, Abnormal

Terme préférentiel

Fibrinogens, Abnormal  

Type

  • mesh:Descriptor

Définition

  • Fibrinogens which have a functional defect as the result of one or more amino acid substitutions in the amino acid sequence of normal fibrinogen. Abnormalities of the fibrinogen molecule may impair any of the major steps involved in the conversion of fibrinogen into stabilized fibrin, such as cleavage of the fibrinopeptides by thrombin, polymerization and cross-linking of fibrin. The resulting dysfibrinogenemias can be clinically silent or can be associated with bleeding, thrombosis or defective wound healing.

Concept générique

Synonyme(s)

  • Abnormal Fibrinogens

Qualificatif(s) autorisé(s)

Traductions

URI

http://data.loterre.fr/ark:/67375/JVR-DLR753LR-L

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RDF/XML TURTLE JSON-LD Date de création 16/05/1988, dernière modification le 30/06/2018