Concept information
Terme préférentiel
Cisplatin
Type
-
mesh:Descriptor
Définition
- An inorganic and water-soluble platinum complex. After undergoing hydrolysis, it reacts with DNA to produce both intra and interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity of cisplatin correlates with cellular arrest in the G2 phase of the cell cycle.
Concept générique
Synonyme(s)
- 15663-27-1 (Cisplatin)
- cis-Diamminedichloroplatinum
- cis-Diamminedichloroplatinum(II)
- cis-Dichlorodiammineplatinum(II)
- cis-Platinum
- Dichlorodiammineplatinum
- Platinum, diamminedichloro-, (SP-4-2)-
- Platinum Diamminodichloride
- Q20Q21Q62J
Qualificatif(s) autorisé(s)
- administration & dosage (Qualifier)
- adverse effects (Qualifier)
- agonists (Qualifier)
- analogs & derivatives (Qualifier)
- analysis (Qualifier)
- antagonists & inhibitors (Qualifier)
- blood (Qualifier)
- cerebrospinal fluid (Qualifier)
- chemical synthesis (Qualifier)
- chemistry (Qualifier)
- classification (Qualifier)
- economics (Qualifier)
- history (Qualifier)
- immunology (Qualifier)
- isolation & purification (Qualifier)
- metabolism (Qualifier)
- pharmacokinetics (Qualifier)
- pharmacology (Qualifier)
- poisoning (Qualifier)
- radiation effects (Qualifier)
- standards (Qualifier)
- supply & distribution (Qualifier)
- therapeutic use (Qualifier)
- toxicity (Qualifier)
- urine (Qualifier)
Action(s) pharmacologique(s)
Traductions
-
français
-
15663-27-1 (Cisplatin)
-
cis-Diamminedichloroplatine(II)
-
cis-Platine
-
Platinum, diamminedichloro-, (SP-4-2)-
-
Q20Q21Q62J
URI
http://data.loterre.fr/ark:/67375/JVR-DPTS7TDV-D
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