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Concept information

Amino Acids, Peptides, and Proteins > Proteins > DNA-Binding Proteins > Tumor Suppressor p53-Binding Protein 1
Amino Acids, Peptides, and Proteins > Proteins > Nucleoproteins > Chromosomal Proteins, Non-Histone > Tumor Suppressor p53-Binding Protein 1
Amino Acids, Peptides, and Proteins > Proteins > Nuclear Proteins > Chromosomal Proteins, Non-Histone > Tumor Suppressor p53-Binding Protein 1

Terme préférentiel

Tumor Suppressor p53-Binding Protein 1  

Type

  • mesh:Descriptor

Définition

  • A nuclear and cytoplasmic protein that associates with KINETOCHORES and contains a C-terminal TUDOR DOMAIN. It plays a critical role in the cellular response to DNA DAMAGE and localizes to DOUBLE-STRAND DNA BREAKS. It may also function in M PHASE CELL CYCLE CHECKPOINTS and as an enhancer of TUMOR SUPPRESSOR PROTEIN P53-mediated transcriptional activation.

Concept générique

Synonyme(s)

  • 53BP1 Protein
  • p202 Protein
  • TP53BP1 Protein
  • Tumor Protein p53-Binding Protein, 1

Qualificatif(s) autorisé(s)

Traductions

URI

http://data.loterre.fr/ark:/67375/JVR-F9612WCQ-X

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RDF/XML TURTLE JSON-LD Date de création 08/07/2016, dernière modification le 05/07/2016