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Concept information

Terme préférentiel

Solute Carrier Organic Anion Transporter Family Member 1B3  

Type

  • mesh:Descriptor

Définition

  • A sodium-independent organic anion transporter that functions in the uptake of various drugs and endogenous compounds including ESTRADIOL; TAUROCHOLATE; LEUKOTRIENE C4; and METHOTREXATE. It also functions in clearing BILE ACIDS and organic anions from the liver. Mutations in the SLCO1B3 gene are associated with Rotor Type HYPERBILIRUBINEMIA.

Synonyme(s)

  • Liver-Specific Organic Anion Transporter-2
  • OATP1B3 Protein
  • OATP8 Protein
  • SLC21A8 Protein
  • SLCO1B3 Protein
  • Solute Carrier Family 21 Member 8 Protein

Traductions

URI

http://data.loterre.fr/ark:/67375/JVR-F981D93F-X

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RDF/XML TURTLE JSON-LD Date de création 11/07/2017, dernière modification le 06/04/2017