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Concept information

Terme préférentiel

Hypophosphatasia  

Type

  • mesh:Descriptor

Définition

  • A genetic metabolic disorder resulting from serum and bone alkaline phosphatase deficiency leading to hypercalcemia, ethanolamine phosphatemia, and ethanolamine phosphaturia. Clinical manifestations include severe skeletal defects resembling vitamin D-resistant rickets, failure of the calvarium to calcify, dyspnea, cyanosis, vomiting, constipation, renal calcinosis, failure to thrive, disorders of movement, beading of the costochondral junction, and rachitic bone changes. (From Dorland, 27th ed)

Traductions

URI

http://data.loterre.fr/ark:/67375/JVR-G9LKRLB5-7

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RDF/XML TURTLE JSON-LD Date de création 01/01/1999, dernière modification le 08/07/2013