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Concept information

Terme préférentiel

Inhibitor of Growth Protein 1  

Type

  • mesh:Descriptor

Définition

  • A nuclear protein and tumor suppressor that contains a C-terminal PHD ZINC FINGER. It is expressed in different isoforms in various tissues and interacts with TUMOR SUPPRESSOR PROTEIN P53 to negatively regulate cell growth. Reduced expression and chromosomal rearrangements of the ING1 gene are associated with different cancers including HEAD AND NECK NEOPLASMS.

Synonyme(s)

  • ING-1 Protein
  • ING1 Protein
  • p33ING Protein

Traductions

URI

http://data.loterre.fr/ark:/67375/JVR-GLK1B94T-K

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RDF/XML TURTLE JSON-LD Date de création 11/07/2017, dernière modification le 29/06/2017