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Concept information

Terme préférentiel

RNA-Binding Protein EWS  

Type

  • mesh:Descriptor

Définition

  • A ubiquitous hnRNP protein that contains an RNA RECOGNITION MOTIF and C-terminal ranBP2-type zinc finger. It localizes to the CELL NUCLEUS and CYTOPLASM and is expressed as different isoforms in various tissues, interacting with CALMODULIN and TUMOR SUPPRESSOR PROTEIN P53 to negatively regulate cell growth. Translocations that result in the formation of fusion proteins containing parts of RNA-binding protein EWS are associated with EWING SARCOMA.

Synonyme(s)

  • Ewing Sarcoma Breakpoint Region 1 Protein
  • Ewing Sarcoma Breakpointregion 1 Protein
  • EWS Protein
  • EWS Proto-Oncogene Protein
  • EWSR1 Protein
  • EWS RNA Binding Protein 1

Traductions

URI

http://data.loterre.fr/ark:/67375/JVR-GTZLS67Q-4

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RDF/XML TURTLE JSON-LD Date de création 03/07/2002, dernière modification le 29/06/2017